“Tuberculosis: the persistent global scourge of humanity” with speaker Dr Lalita Ramakrishnan on 26 May 2022 at 18:00 (IST) 

Respondent: Joseph Keane MRIA, Professor of Medicine, Trinity College Dublin

Tuberculosis (TB) is an ancient disease that has killed more people than any other infectious disease. Despite more than 60 years of antibiotics, TB remains a major cause of sickness and death and was the second largest infectious killer in 2020 after Covid-19. New drugs and an effective vaccine are desperately needed. To better understand the disease pathogenesis, we have developed the zebrafish as a model of TB. In early life, the zebrafish is transparent, and we have used this feature to examine how the TB bacterium evades and exploits host immune cells in real-time in live animals. Then, by manipulating zebrafish genes, we have uncovered the genetic and mechanistic bases of the disease. This has led us to a new understanding of host genetic susceptibilities and potentials for new anti-TB drugs that we are showing are relevant for humans too.

Tickets are free and are available through the Eventbrite Booking System. Note that this is an online event.

Dr Lalita Ramakrishnan is Professor of Immunology and Infectious Diseases at the
University of Cambridge, UK. She received her medical degree from the Baroda
Medical College in India, and her PhD in Immunology from Tufts University in
Boston. After completing medical training and a fellowship in Infectious Diseases she
moved to Stanford University as a postdoctoral fellow where she began her research
into TB. She then joined the faculty at the University of Washington, where she
developed a zebrafish model for tuberculosis. In 2014, she moved to the University of
Cambridge and her laboratory continues to study TB pathogenesis. Professor
Ramakrishnan has received several awards and honours, including the NIH Director’s
Pioneer Award and the Wellcome Trust Principal Research Fellowship. She is a
member of the US National Academy of Sciences and EMBO and a Fellow of the Royal
Society and Academy of Medical Sciences.

The French Foundation for Rare Diseases (FFRD) has codeveloped, in collaboration with European Reference Networks Genturis and Ithaca, in the context of the European Joint Programme for Rare Diseases EJPRD a MOOC (Massive Open Online Course) completely free named “Diagnosing Rare Diseases: from the Clinic to the Research and back”.

The third session will start next Monday April, 18th andis now open for enrollment:


Here below the topics covered:

·         The diagnostic process and the types of genetic tests available for rare diseases

·         The differences in rare genetic diseases patient pathways

·         Technological advances for diagnostic research

·         The role of collaborative studies and data sharing in rare diseases diagnosis

·         The impact of having a diagnosis or lacking a diagnosis on patients’ lives

·         The role and place of physiopathology approaches as well as social sciences research in the context of rare diseases diagnosis.

·         Learners will gain insight into patients’ experiences, will discuss key issues relating to this topic and will also have the possibility to undertake their own internet-based investigations.

The course is designed for individuals with a keen interest in diagnostic research and rare diseases.

Health Research Charities Ireland invites you to an upcoming Irish Health Research Forum event:

Embedding research in the Irish health service
09:30 – 13:00, Wednesday, 11th May, 2022
In person: The Spencer Hotel, IFSC

About this event

HRCI is delighted to welcome attendees back to an in-person Irish Health Research Forum meeting on May 11th.

This event will bring together researchers, healthcare professionals, patients, policy makers, funders, industry representatives and many more, to consider how we can instil a culture of research within the Irish health service. A portion of the morning will involve discussion groups, enabling you to share your perspectives and providing a much-needed chance for in-person chat and networking.

Due to the discussion-based nature of the event, a hybrid option is not possible. However, we will record the talks and share them afterwards.

Date: Wednesday, 11th May
Time: 9.30am-13.00pm
Registration is essential: Please click here
Location: The Spencer Hotel, Excise Walk, International Financial Services Centre,  Dublin 1, D01 X4C9

We are delighted to have some inspiring contributors lined up, including:

  • Prof Philip Nolan; Director General, Science Foundation Ireland 
  • Prof Paul McNally; Director, Research & Innovation, Children’s Health Ireland / Associate Professor of Paediatrics, RCSI University of Medicine & Health Sciences / Consultant in Respiratory Medicine, CHI
  • Dr Ana Terres; Head of Research and Evidence, Assistant National Director, Health Service Executive 
  • Dr Sarah McLoughlin; Patient Advocate 
  • Prof Rachel Crowley; Consultant Endocrinologist, St. Vincent’s University Hospital / Clinical Professor UCD

Please register for the event here

We hope you can join us,

The team at HRCI

Read the latest report of the IHRF on Health Reseach.
Their conclusions will be music to your ears!

The 8th Joint Dutch/UK Clinical Genetics Societies and Cancer Genetics Groups meeting is being held online on 7th – 8th March 2022. Many excellent abstracts were submitted by both UK and Dutch participants and we are pleased to inform you that a diverse and high-quality program has been put together by our scientific committee.


The central theme of the 8th joint meeting is: “Next Generation Genetics”. The updated program (Central European Time) is now available: https://www.aanmelder.nl/jointmeeting/program and includes presentations on all topics across the field of clinical genetics. Joint sessions are planned with the UK/ Dutch Cancer Genetics Groups. A separate session at the end of day two is scheduled for the Ben ter Haar Prize. 


Registration for this online event is open via the website: https://www.aanmelder.nl/jointmeeting/subscribe

Registration fees:
– Joint meeting (2 days): €125 / £105 
– Dysmorphology meeting: no cost
– Cancer Genetics case day: no cost

Joint Dutch/ UK Cancer Cases Day – Wednesday 9th March

For the first time we will also be holding a joint cancer cases day. There are slots for both Dutch and UK cases (each case 10 minutes). Teams will be used as a platform for this meeting. Only colleagues with an email-address referring to a hospital can register for this meeting. 

Known or complex unsolved cases are encouraged.

Cases from the Netherlands

Regarding the Netherlands every separate genetic centre will be asked to prepare one or two cases, time to present is limited to 10 minutes including discussion.

Cases from the UK

There are a total of 9 slots for UK cases (each of 10 minutes). If more than 9 cases are received, we will select the most interesting /varied from those submitted and those not selected can be presented at one of the UK CGG National MDT meetings.

If you would like to present a case (UK only), please submit your case to terri.mcveigh@rmh.nhs.uk by February 28th 2022 in the form of a PowerPoint presentation of no more than 6 slides. Please ensure that no identifiable information is included. 

Registration for this event is open now via the website: https://www.aanmelder.nl/jointmeeting/subscribe

Dutch/UK Dysmorphology Meeting – Wednesday 9th March

We will be holding a Dysmorphology meeting jointly with both UK and Dutch participants. Teams will be used as a platform for this meeting. Only colleagues with an email-address referring to a hospital can register for this meeting.

Registration for this event is open now via the website: https://www.aanmelder.nl/jointmeeting/subscribe

If you would like to present a case, please register for the meeting at the website and submit your cases (short abstract and a PowerPoint presentation of no more than 5 slides) to dysmo@gosh.nhs.uk by Friday 4th March at latest. We can accept up to 2 – 3 cases per centre. Please ensure that no identifiable information is included. 

BSGM Membership Services
Follow us on Twitter | Find us on Facebook | Manage your membership via mySociety

This year All Ireland virtual rare disease research symposium is scheduled to take place on the 25th of February 13.00-17.00 (GMT) to raise awareness of “Rare Diseases Day 2022”.  This event is building on our existing patient public involvement (PPI) and research partnerships across the north (RARDTAC) and south (RAINDROP). This virtual symposium will inspire and empower early-career researchers also create strategic transdisciplinary networks to promote world-class rare disease educational developments, research, innovation and engagement in Ireland.

Register here: https://ucd-ie.zoom.us/webinar/register/WN_CjG11L7FQ26o-dh4PBMzJw

The ISHG is pleased to share the recently published HRCI publication ‘Using data for better health research’

This course will take place virtually with speakers presenting in the Mater Hospital Dublin on 25-27th April.

Winners of the 2021 National DNA Day Schools Essay Writing Competition, and details of the 2022 Competition.